COSENTYX treats ankylosing spondylitis in an innovative way. It’s the first medicine of its kind to target IL-17A, one of the many proteins that may be involved in causing an overactive—or noisy—immune system. COSENTYX helps “quiet the noise” in your immune system by targeting IL-17A, and may help you feel better.


Most people who took COSENTYX not only had less spinal pain and stiffness, they also saw improvement in their ability to move, and felt better overall after just 16 weeks compared to placebo. A similar percentage of people saw improvement at 4 years as well. Learn more.


In this study, patients and doctors were told which medication was being used after 4 months. When patients and doctors know the study drug being used, it may affect the results.

How long has COSENTYX been on the market?

COSENTYX was approved by the FDA in January 2015 to treat moderate to severe plaque psoriasis, and in January 2016 to treat active psoriatic arthritis and active ankylosing spondylitis. COSENTYX has already been prescribed to over 115,000 people in the United States.


COSENTYX has been studied extensively for 12 years in dozens of clinical trials. More clinical trials are still ongoing as we stay committed to studying COSENTYX for people with PsO, PsA, and AS.


Across all indications.

What makes COSENTYX different?

COSENTYX is a different kind of targeted biologic. It’s the first and most commonly prescribed treatment of its kind§ and works within your body to target the IL-17A protein, which is thought to be one of the proteins to play a role in causing inflammation.


“We know there are multiple pathways and multiple proteins involved in inflammation. IL-17A is one of these proteins that could be overproduced in plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. COSENTYX specifically targets IL-17A. Because it’s this specific pathway, that’s the reason it may be different from most other biologics.”

—Dr. Elizabeth Perkins, a Practicing Rheumatologist


Watch more


§Most prescribed IL-17A treatment across all indications.

How do I take COSENTYX?

COSENTYX is taken by injection, either with the Sensoready® Pen device or a prefilled syringe. Your doctor will show you how to take your medication. To help you feel more comfortable or for an injection refresher, make sure to check out the helpful videos and tools below.  


How to use the Sensoready Pen

See real patients using the Sensoready Pen 

Download the Sensoready Pen quick tips brochure so you have it handy.


How to use the prefilled syringe

How do I inject?

A healthcare provider will show you how to prepare and inject COSENTYX properly before you use it for the first time. If you need a refresher, you can watch our injection demonstration videos or sign up for live virtual injection training by calling 1-844-COSENTYX (1-844-267-3689).


You can also download the Sensoready Pen quick tips brochure so you have it handy.

What’s the dosing?

COSENTYX is a convenient once-a-month dose. The recommended dose is 150 mg, which is taken as 1 injection under the skin. To start, your doctor may either prescribe 5 weekly doses or just one dose every 4 weeks, based on what’s right for you. After that, you only need to take COSENTYX every 4 weeks.


Find out more about dosing for ankylosing spondylitis.

What are the most common side effects?

The most common side effects may include: cold symptoms, diarrhea, nausea, and upper respiratory infections. Keep in mind, these are not all of the possible side effects of COSENTYX. Call your doctor for medical advice about side effects. Here’s additional information about safety for COSENTYX.

How well will it work?

Individual results may vary. Most people who took COSENTYX not only had less spinal pain and stiffness, they also saw improvement in their ability to move, and felt better overall after just 16 weeks compared to placebo. A similar percentage of people saw improvement at 4 years as well. Learn more.


In this study, patients and doctors were told which medication was being used after 4 months. When patients and doctors know the study drug being used, it may affect the results. 

When will it start working?

Individual results may vary. At 16 weeks, approximately 6 out of 10 people noticed at least a 20% improvement in overall symptoms of AS. See COSENTYX clinical trial results.


About 61% of patients saw this level of improvement versus 28% taking placebo. 

What is the COSENTYX® Connect Personal Support Program?

COSENTYX® Connect is a free dedicated support program for everyone taking COSENTYX, or for those who want to learn more about COSENTYX. When you sign up, you’ll be able to take advantage of the great tools and resources available exclusively through COSENTYX® Connect.


Cosentyx Connect Personal Support Program


For those who are prescribed COSENTYX, these benefits include:

  • A dedicated support specialist to help you understand your insurance coverage and what your out-of-pocket costs might be, set up your $0 co-pay,* and check in from time to time throughout your first year of treatment
  • $0 co-pay* if you’re eligible
  • Up to two years of free medication, while you work with your commercial health plan to secure coverage for COSENTYX Learn more
  • A Welcome Kit with tools, including a travel kit, and other resources to help you get started
  • A recyclable sharps container
  • Injection training support
  • Personalized support and resources via mail, e-mail, or text
  • Consumer Brief Summary of Important Safety Information


Learn more or call 1-844-COSENTYX (1-844-267-3689) with questions.

Will my insurance cover it?

If you have commercial insurance, COSENTYX® Connect or your specialty pharmacy will conduct a benefits investigation to see whether your insurance covers COSENTYX and what your out-of-pocket costs might be.  


Covered until you're covered


If you have commercial or private insurance, and your coverage is initially denied, you may get up to 2 years of COSENTYX for free through COSENTYX® Connect while you continue to work with your insurance company to resubmit for coverage.


Questions? Please call us at 1-844-COSENTYX (1-844-267-3689) or download the Insurance Coverage Questions brochure.

How do I get a $0 co-pay?

$0 Co-Pay

Many people pay nothing* for a 30-day prescription of COSENTYX with our $0 co-pay program. For people with commercial or private insurance whose plan covers COSENTYX.  Click here to register for a $0 co-pay or call 1-855-823-2886.

What if I don’t qualify for the $0 co-pay* or the Covered Until You’re Covered Program?

Visit Novartis Patient Assistance NOW to get assistance with finding programs that may help you with your Novartis prescription medications. Learn more at www.patientassistancenow.com or by calling 1-800-277-2254.

*Limitations apply. Up to a $16,000 annual limit. Offer not valid under Medicare, Medicaid, or any other federal or state program. Novartis reserves the right to rescind, revoke, or amend this program without notice. See complete Terms & Conditions for details.

Covered Until You're Covered Program: Eligible patients must have commercial insurance, a valid prescription for COSENTYX, and a denial of insurance coverage based on a prior authorization request. Program requires the submission of an appeal of the coverage denial within the first 90 days of enrollment in order to remain eligible. Program provides initial 5 weekly doses (if prescribed) and monthly doses for free to patients for up to two years or until they receive insurance coverage approval, whichever occurs earlier. Program is not available to patients whose medications are reimbursed in whole or in part by Medicare, Medicaid, TRICARE, or any other federal or state program. Patients may be asked to re-verify insurance coverage status during the course of the program. No purchase necessary. Program is not health insurance, nor is participation a guarantee of insurance coverage. Limitations may apply. Enrolled patients awaiting coverage for COSENTYX after two years may be eligible for a limited Program extension. Novartis Pharmaceuticals Corporation reserves the right to rescind, revoke, or amend this Program without notice. Program enrollment must occur by 12/31/19.

View more
View less

COSENTYX® (secukinumab) is a prescription medicine used to treat adults:

  • with moderate to severe plaque psoriasis that involves large areas or many areas of the body, and who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light, alone or with systemic therapy)

  • with active psoriatic arthritis

  • with active ankylosing spondylitis

Important Safety Information

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:


COSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections.

  • Your doctor should check you for tuberculosis (TB) before starting treatment with COSENTYX.
  • If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.
  • Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX. Do not take COSENTYX if you have an active TB infection.

Before starting COSENTYX, tell your doctor if you:

  • are being treated for an infection
  • have an infection that does not go away or that keeps coming back
  • have TB or have been in close contact with someone with TB
  • think you have an infection or have symptoms of an infection, such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarrhea or stomach pain; burning when you urinate or urinate more often than normal

After starting COSENTYX, call your doctor right away if you have any signs of infection listed above. Do not use COSENTYX if you have any signs of infection unless you are instructed to by your doctor.

Inflammatory Bowel Disease

New cases of inflammatory bowel disease or “flare-ups” can happen with COSENTYX, and can sometimes be serious. If you have inflammatory bowel disease (ulcerative colitis or Crohn’s disease), tell your doctor if you have worsening disease symptoms during treatment with COSENTYX or develop new symptoms of stomach pain or diarrhea.

Serious Allergic Reactions

Serious allergic reactions can occur. Get emergency medical help right away if you get any of the following symptoms: feeling faint; swelling of your face, eyelids, lips, mouth, tongue, or throat; trouble breathing or throat tightness; chest tightness; or skin rash. If you have a severe allergic reaction, do not give another injection of COSENTYX.  

Before starting COSENTYX, tell your doctor if you:

  • have any of the conditions or symptoms listed above for infections
  • have inflammatory bowel disease (Crohn's disease or ulcerative colitis)
  • are allergic to latex. The needle caps contain latex.
  • have recently received or are scheduled to receive an immunization (vaccine). People who take COSENTYX should not receive live vaccines.
  • have any other medical conditions
  • are pregnant or plan to become pregnant. It is not known if COSENTYX can harm your unborn baby. You and your doctor should decide if you will use COSENTYX.
  • are breastfeeding or plan to breastfeed. It is not known if COSENTYX passes into your breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of your medicines to show your doctor and pharmacist when you get a new medicine.

How should I use COSENTYX?

See the detailed Instructions for Use that comes with your COSENTYX for information on how to prepare and inject a dose of COSENTYX, and how to properly throw away (dispose of) used COSENTYX Sensoready® pens and prefilled syringes.

  • Use COSENTYX exactly as prescribed by your doctor.
  • If your doctor decides that you or a caregiver may give your injections of COSENTYX at home, you should receive training on the right way to prepare and inject COSENTYX. Do not try to inject COSENTYX yourself, until you or your caregiver has been shown how to inject COSENTYX by your doctor or nurse.

The most common side effects of COSENTYX include: cold symptoms, diarrhea, and upper respiratory infections. These are not all of the possible side effects of COSENTYX. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

 Please see full Prescribing Information, including Medication Guide.