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For adults with active ankylosing spondylitis

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HOW DOES COSENTYX WORK FOR AXIAL SPONDYLOARTHRITIS (axSpA)??

Watch the video to see how COSENTYX is thought to work to help people with ankylosing spondylitis (AS).†

Did you know an overactive immune system is like an overactive tennis ball machine? There are multiple molecules in the body that may play a role in causing inflammation. The IL-17A molecule is just one of them.

Patient portrayal of how COSENTYX works.
†The relationship between how COSENTYX works in the body and how it affects your symptoms is unknown.

COSENTYX is proven to reduce the overall symptoms of AS:

16 WKS

In as little as 16 weeks, twice as many people treated with COSENTYX achieved at least a 20% improvement in overall symptoms versus those taking placebo (61% vs 28%). Many not only had more back pain relief,‡ but also saw an improvement in their ability to move.§

5 YRS

A similar percentage of people saw improvement at 5 years as well.†

‡At Week 16, patients who completed a questionnaire that asked how difficult it was to perform physical activities saw 43% improvement in back pain while taking COSENTYX vs. 16% taking placebo.
§At 16 weeks, patients saw 35% improvement in mobility while taking COSENTYX vs. 11% taking placebo.
†In this study, patients and doctors were told which medication was being used after 4 months. When patients and doctors know the study drug being used, it may affect the results.

 

COSENTYX Experience

COSENTYX has a well-studied safety profile. In 2015, COSENTYX was FDA approved to treat adults with moderate to severe plaque psoriasis. In 2016, it was FDA approved to treat active ankylosing spondylitis and active psoriatic arthritis in adults. Then, it was approved in 2020 to treat adults with non-radiographic axial spondyloarthritis. It has since been approved to treat children with plaque psoriasis (6 years and older), psoriatic arthritis (2 years and older), and enthesitis-related arthritis (4 years and older).

#1

COSENTYX is the #1 prescribed treatment of its kind†

3.7m

Over 3.7 million prescriptions of COSENTYX have been filled† in the United States

15 YRS

COSENTYX has been studied for over 15 years in dozens of clinical trials

†Across all indications combined.

Improved mobility

“There’s a noticeable difference. I’m feeling much better.”

—Wendy, Actual Patient

Individual results may vary. Wendy was compensated for her time.

Less morning stiffness

“I’m able to get up in the mornings and not feel that stiffness as strongly as I had before.”

—Jesse, Actual Patient

Individual results may vary. Jesse was compensated for his time.

Back pain relief

“I got relief fairly quickly. I was no longer having incredible back pain.”

—Garth, Actual Patient

Individual results may vary. Garth was compensated for his time.

Dr Perkins Head Shot

Dr Perkins was compensated for her time.

Watch as Dr Elizabeth Perkins explains how COSENTYX can help people with AS feel better.

"I hope that more patients will get diagnosed sooner and understand what’s going on with their body, and this whole journey is a little bit easier."

WATCH NOW

Tap to see IMPORTANT SAFETY INFORMATION AND APPROVED USES

IMPORTANT SAFETY INFORMATION

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

What is the most important information I should know about COSENTYX?

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as…

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

What is the most important information I should know about COSENTYX?

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:

Infections

COSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections. Some people have died from these infections.

  • Your doctor should check you for tuberculosis (TB) before starting treatment with COSENTYX.

  • If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.

  • Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX. Do not use COSENTYX if you have an active TB infection.

Before starting COSENTYX, tell your doctor if you:

  • are being treated for an infection

  • have an infection that does not go away or that keeps coming back

  • have TB or have been in close contact with someone with TB

  • think you have an infection or have symptoms of an infection such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarrhea or stomach pain; burning when you urinate or urinate more often than normal

After starting COSENTYX, call your doctor right away if you have any signs of infection listed above. Do not use COSENTYX if you have any signs of infection unless you are instructed to by your doctor.

What are the possible side effects of COSENTYX?

COSENTYX may cause serious side effects, including: 

Serious allergic reactions

Serious allergic reactions can occur. Get emergency medical help right away if you get any of the following symptoms: feeling faint; swelling of your face, eyelids, lips, mouth, tongue, or throat; trouble breathing or throat tightness; chest tightness; skin rash or hives (red, itchy bumps).

If you have a severe allergic reaction, do not give another injection of COSENTYX.

Inflammatory bowel disease

New cases of inflammatory bowel disease or "flare-ups" can happen with COSENTYX, and can sometimes be serious. If you have inflammatory bowel disease (ulcerative colitis or Crohn's disease), tell your doctor if you have worsening disease symptoms during treatment with COSENTYX or develop new symptoms of stomach pain or diarrhea.

Severe skin reactions that look like eczema can happen during treatment with COSENTYX from days to months after your first dose and can sometimes lead to hospitalization. Your doctor may temporarily stop treatment with COSENTYX if you develop severe skin reactions. Tell your doctor if you have any of the following signs or symptoms: redness or rash; itching; small bumps or patches; your skin is dry or feels like leather; blisters on the hands or feet that ooze or become crusty or skin peeling.

The most common side effects of COSENTYX include: cold symptoms, diarrhea, and upper respiratory tract infections.

These are not all of the possible side effects of COSENTYX. Call your doctor for medical advice about side effects.

Before using COSENTYX, tell your doctor if you:

  • have any of the conditions or symptoms listed above for infections.

  • have inflammatory bowel disease (Crohn's disease or ulcerative colitis).

  • are allergic to latex. The needle cap on the COSENTYX Sensoready® pen, and 150 mg/mL and 75 mg/0.5 mL prefilled syringes contains latex.

  • have recently received or are scheduled to receive an immunization (vaccine). People who take COSENTYX should not receive live vaccines. Children should be brought up to date with all vaccines before starting COSENTYX.

  • have any other medical conditions and all the medicines you take, including prescription and over‑the‑counter medicines, vitamins, and herbal supplements. Keep a list of your medicines to show your healthcare provider and pharmacist when you get a new medicine.

  • are pregnant or plan to become pregnant. It is not known if COSENTYX can harm your unborn baby. You and your doctor should decide if you will use COSENTYX.

  • are breastfeeding or plan to breastfeed. It is not known if COSENTYX passes into your breast milk.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch ↗, or call 1-800-FDA-1088 ↗.

Please see full Prescribing Information ↗, including Medication Guide ↗.

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INDICATIONS

COSENTYX® (secukinumab) is a prescription medicine used to treat:

  • people 6 years of age and older with moderate to severe plaque psoriasis (PsO) that involves large areas or many areas of the body, and who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light alone or with systemic therapy)…

COSENTYX® (secukinumab) is a prescription medicine used to treat:

  • people 6 years of age and older with moderate to severe plaque psoriasis (PsO) that involves large areas or many areas of the body, and who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light alone or with systemic therapy)

  • people 2 years of age and older with active psoriatic arthritis (PsA)

  • adults with active ankylosing spondylitis (AS)

  • adults with active non-radiographic axial spondyloarthritis (nr-axSpA) and objective signs of inflammation 

  • people 4 years of age and older with active enthesitis-related arthritis (ERA)

  • adults with moderate to severe hidradenitis suppurativa (HS)

Click or scroll to see IMPORTANT SAFETY INFORMATION AND APPROVED USES
*Limitations apply. Valid only for those with private insurance. Program provides up to $16,000 annually for the cost of COSENTYX and up to $150 per infusion (up to $1,950 annually) for the cost of administration. Co-pay support for infusion administration cost not available in Rhode Island or Massachusetts. Offer not valid under Medicare, Medicaid, or any other federal or state program. Novartis reserves the right to rescind, revoke, or amend this program without notice. See complete Terms & Conditions for details.