What makes COSENTYX® different?

COSENTYX is a biologic that reduces the symptoms of AS, like back pain and morning stiffness. It's the first biologic of its kind to treat AS by targeting a protein called IL-17A.

What is a biologic?

A biologic is a protein-based medication that is made from living sources and is taken by injection or infusion.

What is IL-17A?

The inflammation from AS is like an overactive orchestra. When every instrument is playing loudly—and at once—it sounds more like noise, and less like music. IL-17A is one of the many proteins that may be involved in causing an overactive—or noisy—immune system. COSENTYX helps “quiet the noise” in your immune system by targeting IL-17A, and may help you feel better.

Watch Dr. Perkins explain how COSENTYX works within the body to target IL-17A

 

Real results. Real relief.

16 WKS

Many people who took COSENTYX not only had less spinal pain and morning stiffness, they also saw improvement in their ability to move and felt better overall after just 16 weeks compared to placebo.

4 YRS

A similar percentage of people saw improvement at 4 years as well.

In this study, patients and doctors were told which medication was being used after 4 months. When patients and doctors know the study drug being used, it may affect the results.

COSENTYX is proven to reduce symptoms of AS

In as little as 16 weeks, twice as many people treated with COSENTYX achieved at least a 20% improvement in overall symptoms versus those taking placebo (61% vs. 28%). A similar percentage of people saw an improvement at 4 years as well.

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Garth
Actual Patient

Individual results may vary. Garth was compensated for his time.

Back pain

“I got relief fairly quickly. I was no longer having incredible back pain.”

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Reduced mobility

“There’s a noticeable difference. I’m feeling much better.”

WENDY

Individual results may vary. Wendy was compensated for her time.

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Morning stiffness

“I’m able to get up in the mornings and not feel that stiffness as strong as I had before.”

JESSE

Individual results may vary. Jesse was compensated for his time.

Sensoready Pen

How often is COSENTYX taken for AS?

COSENTYX is a convenient once-a-month dose

Taking your AS medication once a month gives you fewer interruptions in your daily routine. Just one convenient monthly dose of COSENTYX may help relieve symptoms of ankylosing spondylitis. COSENTYX dosing is with or without a loading dose.

To start, your doctor will either prescribe 5 weekly doses or just one dose once a month, based on what's right for you. After that, you only need to take COSENTYX once a month. The recommended dose is 150 mg, which is taken as one injection under the skin.

Your healthcare provider should show you how to prepare and inject COSENTYX before you use it for the first time.

Monthly dose equals 1 dose every 4 weeks.

Only 1% experienced injection site reactions

One percent of people in ankylosing spondylitis clinical trials experienced injection site reactions.

You can download this handy brochure with instructions and tips on injecting so you have them whenever you need them.

About us

COSENTYX has been studied extensively for 12 years across all indications. COSENTYX was approved by the FDA in January 2015 to treat moderate to severe plaque psoriasis. Then in January 2016 it was approved by the FDA to treat active ankylosing spondylitis and active psoriatic arthritis. It has been prescribed to over 115,000 people in the US across all indications.

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Real people with AS aren’t backing down—they’re fighting back with COSENTYX.

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Indications

COSENTYX® (secukinumab) is a prescription medicine used to treat adults:

  • with moderate to severe plaque psoriasis that involves large areas or many areas of the body, and who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light, alone or with systemic therapy)

  • with active psoriatic arthritis

  • with active ankylosing spondylitis

Important Safety Information

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:

Infections

COSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections.

  • Your doctor should check you for tuberculosis (TB) before starting treatment with COSENTYX.
  • If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.
  • Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX. Do not take COSENTYX if you have an active TB infection.

Before starting COSENTYX, tell your doctor if you:

  • are being treated for an infection
  • have an infection that does not go away or that keeps coming back
  • have TB or have been in close contact with someone with TB
  • think you have an infection or have symptoms of an infection, such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarrhea or stomach pain; burning when you urinate or urinate more often than normal

After starting COSENTYX, call your doctor right away if you have any signs of infection listed above. Do not use COSENTYX if you have any signs of infection unless you are instructed to by your doctor.

Inflammatory Bowel Disease

New cases of inflammatory bowel disease or “flare-ups” can happen with COSENTYX, and can sometimes be serious. If you have inflammatory bowel disease (ulcerative colitis or Crohn’s disease), tell your doctor if you have worsening disease symptoms during treatment with COSENTYX or develop new symptoms of stomach pain or diarrhea.

Serious Allergic Reactions

Serious allergic reactions can occur. Get emergency medical help right away if you get any of the following symptoms: feeling faint; swelling of your face, eyelids, lips, mouth, tongue, or throat; trouble breathing or throat tightness; chest tightness; or skin rash. If you have a severe allergic reaction, do not give another injection of COSENTYX.  

Before starting COSENTYX, tell your doctor if you:

  • have any of the conditions or symptoms listed above for infections
  • have inflammatory bowel disease (Crohn's disease or ulcerative colitis)
  • are allergic to latex. The needle caps contain latex.
  • have recently received or are scheduled to receive an immunization (vaccine). People who take COSENTYX should not receive live vaccines.
  • have any other medical conditions
  • are pregnant or plan to become pregnant. It is not known if COSENTYX can harm your unborn baby. You and your doctor should decide if you will use COSENTYX.
  • are breastfeeding or plan to breastfeed. It is not known if COSENTYX passes into your breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of your medicines to show your doctor and pharmacist when you get a new medicine.

How should I use COSENTYX?

See the detailed Instructions for Use that comes with your COSENTYX for information on how to prepare and inject a dose of COSENTYX, and how to properly throw away (dispose of) used COSENTYX Sensoready® pens and prefilled syringes.

  • Use COSENTYX exactly as prescribed by your doctor.
  • If your doctor decides that you or a caregiver may give your injections of COSENTYX at home, you should receive training on the right way to prepare and inject COSENTYX. Do not try to inject COSENTYX yourself, until you or your caregiver has been shown how to inject COSENTYX by your doctor or nurse.

The most common side effects of COSENTYX include: cold symptoms, diarrhea, and upper respiratory infections. These are not all of the possible side effects of COSENTYX. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

 Please see full Prescribing Information, including Medication Guide.