What makes COSENTYX® different?
COSENTYX is a biologic that reduces the symptoms of AS, like back pain and morning stiffness. It's the first biologic of its kind to treat AS by targeting a protein called IL-17A.
What is a biologic?
A biologic is a protein-based medication that is made from living sources and is taken by injection or infusion.
What is IL-17A?
The inflammation from AS is like an overactive orchestra. When every instrument is playing loudly—and at once—it sounds more like noise, and less like music. IL-17A is one of the many proteins that may be involved in causing an overactive—or noisy—immune system. COSENTYX helps “quiet the noise” in your immune system by targeting IL-17A, and may help you feel better.
Watch Dr. Perkins explain how COSENTYX works within the body to target IL-17A
Real results. Real relief.
Many people who took COSENTYX not only had less spinal pain and morning stiffness, they also saw improvement in their ability to move and felt better overall after just 16 weeks compared to placebo.
A similar percentage of people saw improvement at 4 years as well.†
†In this study, patients and doctors were told which medication was being used after 4 months. When patients and doctors know the study drug being used, it may affect the results.
COSENTYX is proven to reduce symptoms of AS
In as little as 16 weeks, twice as many people treated with COSENTYX achieved at least a 20% improvement in overall symptoms versus those taking placebo (61% vs. 28%). A similar percentage of people saw an improvement at 4 years as well.
“I got relief fairly quickly. I was no longer having incredible back pain.”
“There’s a noticeable difference. I’m feeling much better.”
Individual results may vary. Wendy was compensated for her time.
“I’m able to get up in the mornings and not feel that stiffness as strong as I had before.”
Individual results may vary. Jesse was compensated for his time.
How often is COSENTYX taken for AS?
COSENTYX is a convenient once-a-month dose
Taking your AS medication once a month gives you fewer interruptions in your daily routine. Just one convenient monthly dose of COSENTYX may help relieve symptoms of ankylosing spondylitis. COSENTYX dosing is with or without a loading dose.
To start, your doctor will either prescribe 5 weekly doses or just one dose once a month, based on what's right for you. After that, you only need to take COSENTYX once a month.‡ The recommended dose is 150 mg, which is taken as one injection under the skin.
Your healthcare provider should show you how to prepare and inject COSENTYX before you use it for the first time.
‡Monthly dose equals 1 dose every 4 weeks.
Only 1% experienced injection site reactions
One percent of people in ankylosing spondylitis clinical trials experienced injection site reactions.
You can download this handy brochure with instructions and tips on injecting so you have them whenever you need them.
COSENTYX has been studied extensively for 12 years across all indications. COSENTYX was approved by the FDA in January 2015 to treat moderate to severe plaque psoriasis. Then in January 2016 it was approved by the FDA to treat active ankylosing spondylitis and active psoriatic arthritis. It has been prescribed to over 115,000 people in the US across all indications.
Watch our commercial
Real people with AS aren’t backing down—they’re fighting back with COSENTYX.