Ankylosing Spondylitis Treatment Results

For adults with active ankylosing spondylitis

COSENTYX may help improve mobility and reduce back pain in people with ankylosing spondylitis

3x

It's possible to have 3x improvement in mobility^†

Reported by those in a clinical trial taking COSENTYX and who completed a questionnaire that asked how difficult it was to perform physical activities.^†

2x

Get 2x more back pain relief^‡

^†At 16 weeks, patients saw 35% improvement in mobility while taking COSENTYX vs 11% taking placebo.
^‡At 16 weeks, patients taking COSENTYX saw 43% improvement in back pain vs 16% taking placebo.

Many people taking COSENTYX saw relief from AS symptoms at 16 weeks and a similar percentage at 5 years:

Twice as many people treated with COSENTYX achieved at least a 20% improvement in overall symptoms versus those taking placebo (61% vs 28%) in as little as 16 weeks.

Patients taking COSENTYX saw improvement in overall symptoms overall at five years

A similar percentage of people saw an improvement in AS symptoms at 5 years as well.^§

^§In this study, patients and doctors were told which medication was being used after 4 months. When patients and doctors know the study drug being used, it may affect the results.

COSENTYX may help improve your mobility, so you can do the things you need to do more easily.

In a clinical trial, patients taking COSENTYX completed a questionnaire that asked how difficult it was to perform daily activities, which included:

Watch Real Stories

See how real people taking COSENTYX for ankylosing spondylitis are moving and feeling better.

MARK: WATCH ME NOW - 5 years and counting

Mark was moving and feeling better after a few months. 5 years later, he’s still feeling relief from his ankylosing spondylitis symptoms. See what he’d tell others about getting started.

WENDY: WATCH ME NOW - 5 YEARS AND COUNTING

Wendy is still dancing and feeling good 5 years after starting COSENTYX. See what she'd tell others considering COSENTYX to help treat their ankylosing spondylitis.

Actual COSENTYX patients, compensated for their time.

Real Talk with Dr Elizabeth Perkins

See how real people taking COSENTYX are feeling since starting treatment in this series of doctor – patient conversations.

Dr Perkins was compensated for her time.

Watch Now

Tap to see IMPORTANT SAFETY INFORMATION AND APPROVED USES

IMPORTANT SAFETY INFORMATION

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as…

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:

Infections

COSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections. Some people have died from these infections.

Your doctor should check you for tuberculosis (TB) before starting treatment with COSENTYX.
If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.
Your doctor should watch you closely watch for signs and symptoms of TB during treatment with COSENTYX. Do not take COSENTYX if you have an active TB infection.

Before starting COSENTYX, tell your doctor if you:

are being treated for an infection
have an infection that does not go away or that keeps coming back
have TB or have been in close contact with someone with TB
think you have an infection or have symptoms of an infection such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarrhea or stomach pain; burning when you urinate or urinate more often than normal

After starting COSENTYX, call your doctor right away if you have any signs of infection listed above. Do not use COSENTYX if you have any signs of infection unless you are instructed to by your doctor.

Inflammatory bowel disease

New cases of inflammatory bowel disease or "flare-ups" can happen with COSENTYX, and can sometimes be serious. If you have inflammatory bowel disease (ulcerative colitis or Crohn's disease), tell your doctor if you have worsening disease symptoms during treatment with COSENTYX or develop new symptoms of stomach pain or diarrhea.

Serious allergic reactions

Serious allergic reactions can occur. Get emergency medical help right away if you get any of the following symptoms; feeling faint; swelling of your face, eyelids, lips, mouth, tongue, or throat; trouble breathing or throat tightness; chest tightness; skin rash or hives (red, itchy bumps).

If you have a severe allergic reaction, do not give another injection of COSENTYX.

Severe skin reactions that look like eczema can happen during treatment with COSENTYX from days to months after your first dose and can sometimes lead to hospitalization. Your healthcare provider may temporarily stop treatment with COSENTYX if you develop severe skin reactions. Tell your healthcare provider if you have any of the following signs or symptoms:

redness or rash
itching
small bumps or patches
your skin is dry or feels like leather
blisters on the hands or feet that ooze or become crusty
skin peeling

Before using COSENTYX, tell your doctor if you:

have any of the conditions or symptoms listed above for infections.
have inflammatory bowel disease (Crohn's disease or ulcerative colitis).
are allergic to latex. The needle cap on the COSENTYX Sensoready® pen, and 150 mg/mL and 75 mg/0.5 mL prefilled syringes contains latex.
have recently received or are scheduled to receive an immunization (vaccine). People who take COSENTYX should not receive live vaccines. Children should be brought up to date with all vaccines before starting COSENTYX.
have any other medical conditions.
are pregnant or plan to become pregnant. It is not known if COSENTYX can harm your unborn baby. You and your doctor should decide if you will use COSENTYX.
are breastfeeding or plan to breastfeed. It is not known if COSENTYX passes into your breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of your medicines to show your doctor and pharmacist when you get a new medicine.

How should I use COSENTYX?

Read the detailed Instructions for Use that comes with your COSENTYX for information on how to prepare and inject a dose of COSENTYX, and how to properly throw away (dispose of) used COSENTYX.

Use COSENTYX exactly as prescribed by your doctor.
If your doctor decides that you or a caregiver may give your injections of COSENTYX at home, you should receive training on the right way to prepare and inject COSENTYX. Do not try to inject COSENTYX yourself, until you or your caregiver has been shown how to inject COSENTYX by your doctor or nurse.

The most common side effects of COSENTYX include: cold symptoms, diarrhea, and upper respiratory infections. These are not all of the possible side effects of COSENTYX. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch ↗, or call 1-800-FDA-1088.

Please see full Prescribing Information ↗, including Medication Guide ↗.

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COSENTYX may help improve mobility and reduce back pain in people with ankylosing spondylitis

3x

It's possible to have 3x improvement in mobility^†