Ankylosing Spondylitis Treatment | COSENTYX® (secukinumab)

For adults with active ankylosing spondylitis

Results fast. Relief that can last.*

COSENTYX is proven to help reduce symptoms of ankylosing spondylitis (AS).

*All results shown from clinical trials using subcutaneous (under the skin) injection. The FDA approval of the intravenous (IV) administration (injected into a vein) of COSENTYX is based on data showing that the amount of the medication in your body after it is given directly through IV was within the range that would be seen when given as SC.

See Results

16 WEEKS

In as little as 16 weeks, twice as many people treated with COSENTYX achieved at least a 20% improvement in overall symptoms versus those taking placebo (61% vs 28%).

5 YEARS

A similar percentage of people saw an improvement at 5 years as well.^†

^†In this study, patients and doctors were told which medication was being used after 4 months. When patients and doctors know the study drug being used, it may affect the results.

#1 PRESCRIBED

COSENTYX is the #1 prescribed^§ biologic treatment of its kind.^¶

^§Across all indications.
^¶Treatment for AS that targets IL-17A, one of the multiple molecules in the body that may play a role in inflammation.

Currently taking COSENTYX?

Sign up for COSENTYX® Connect to access a full range of services and support, like a COSENTYX® Connect Team member, the COSENTYX® Connect Co-pay program, if privately insured and otherwise eligible, and injection resources to make your experience with COSENTYX as easy, affordable, and convenient as possible.

How does COSENTYX work?

COSENTYX is the first biologic treatment of its kind to treat ankylosing spondylitis (AS) by specifically targeting and blocking IL-17A, one of the multiple molecules that is believed to play a role in causing inflammation. It’s the first and only treatment to offer both self-injection and IV infusion dosing options that target IL-17A.^#

^#As of January 2024.

Find Out More

WATCH

Mark was moving and feeling better after a few months taking COSENTYX.

Five years later, he’s still feeling relief from his ankylosing spondylitis symptoms. See what he’d tell others about getting started.

For more real stories from real people with AS, click here.

FIND A DOCTOR

Real people taking COSENTYX are moving and feeling better.

Could you be one of them? Find a rheumatologist in your area who has experience prescribing biologics, as well as other treatments for ankylosing spondylitis (AS).

Go Now

MAKE A PLAN

Tell your rheumatologist how you really feel.

Be real about how you feel with your doctor. Use our doctor conversation starter to help you have a better conversation about how ankylosing spondylitis (AS) affects you.

Get Started

See how real people are doing after 5 years on COSENTYX.

Mark and Wendy are moving and feeling better with COSENTYX. Before, their back pain and morning stiffness left them feeling stuck. But with 5 years of relief with COSENTYX, they're moving on.

Mark and Wendy were compensated for their time. Individual results may vary.

Tap to see IMPORTANT SAFETY INFORMATION AND APPROVED USES

IMPORTANT SAFETY INFORMATION

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

What is the most important information I should know about COSENTYX?

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as…

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

What is the most important information I should know about COSENTYX?

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:

Infections

COSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections. Some people have died from these infections.

Your doctor should check you for tuberculosis (TB) before starting treatment with COSENTYX.
If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.
Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX. Do not use COSENTYX if you have an active TB infection.

Before starting COSENTYX, tell your doctor if you:

are being treated for an infection
have an infection that does not go away or that keeps coming back
have TB or have been in close contact with someone with TB
think you have an infection or have symptoms of an infection such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarrhea or stomach pain; burning when you urinate or urinate more often than normal

After starting COSENTYX, call your doctor right away if you have any signs of infection listed above. Do not use COSENTYX if you have any signs of infection unless you are instructed to by your doctor.

What are the possible side effects of COSENTYX?

COSENTYX may cause serious side effects, including:

Serious allergic reactions

Serious allergic reactions can occur. Get emergency medical help right away if you get any of the following symptoms: feeling faint; swelling of your face, eyelids, lips, mouth, tongue, or throat; trouble breathing or throat tightness; chest tightness; skin rash or hives (red, itchy bumps).

If you have a severe allergic reaction, do not give another injection of COSENTYX.

Inflammatory bowel disease

New cases of inflammatory bowel disease or "flare-ups" can happen with COSENTYX, and can sometimes be serious. If you have inflammatory bowel disease (ulcerative colitis or Crohn's disease), tell your doctor if you have worsening disease symptoms during treatment with COSENTYX or develop new symptoms of stomach pain or diarrhea.

Severe skin reactions that look like eczema can happen during treatment with COSENTYX from days to months after your first dose and can sometimes lead to hospitalization. Your doctor may temporarily stop treatment with COSENTYX if you develop severe skin reactions. Tell your doctor if you have any of the following signs or symptoms: redness or rash; itching; small bumps or patches; your skin is dry or feels like leather; blisters on the hands or feet that ooze or become crusty or skin peeling.

The most common side effects of COSENTYX include: cold symptoms, diarrhea, and upper respiratory tract infections.

These are not all of the possible side effects of COSENTYX. Call your doctor for medical advice about side effects.

Before using COSENTYX, tell your doctor if you:

have any of the conditions or symptoms listed above for infections.
have inflammatory bowel disease (Crohn's disease or ulcerative colitis).
are allergic to latex. The needle cap on the COSENTYX Sensoready® pen, and 150 mg/mL and 75 mg/0.5 mL prefilled syringes contains latex.
have recently received or are scheduled to receive an immunization (vaccine). People who take COSENTYX should not receive live vaccines. Children should be brought up to date with all vaccines before starting COSENTYX.
have any other medical conditions and all the medicines you take, including prescription and over‑the‑counter medicines, vitamins, and herbal supplements. Keep a list of your medicines to show your healthcare provider and pharmacist when you get a new medicine.
are pregnant or plan to become pregnant. It is not known if COSENTYX can harm your unborn baby. You and your doctor should decide if you will use COSENTYX.
are breastfeeding or plan to breastfeed. It is not known if COSENTYX passes into your breast milk.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch ↗, or call 1-800-FDA-1088.

Please see full Prescribing Information, including Medication Guide.

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