Plaque Psoriasis Dosing | COSENTYX® (secukinumab)

For people 6+ with moderate to severe plaque psoriasis

Convenient once-a-month dosing^†

The recommended dose of COSENTYX^® (secukinumab) for moderate-severe plaque psoriasis is 300 mg.^† To start, your doctor will prescribe 5 weekly loading doses. To continue after that, you only need to take COSENTYX once a month for maintenance, which means fewer interruptions in your daily routine.

^†Each 300-mg dose is given as 2 injections of 150 mg under the skin. For some people, a dose of 150 mg may be acceptable.

COSENTYX is injected with the Sensoready^® Pen, Unoready^® Pen, or a prefilled syringe. Your healthcare provider should show you how to inject COSENTYX before using it for the first time.

Learn more about our devices and watch step-by-step videos on how to take COSENTYX.

The COSENTYX UnoReady® Pen is designed for comfortable use

Watch How to Use the UnoReady Pen

The COSENTYX UnoReady Pen has a positive satisfaction rating up to 100%.^‡

The UnoReady Pen is a single, 300-mg injection
Design is convenient and easy to use
The needle is hidden
The cap is not made with natural rubber latex
The majority of people experience no pain with the injection^§

Download and print the step-by-step Instructions for Use so you can have them handy whenever you need them. For more information about using the UnoReady Pen or the Sensoready® Pen, download and print the Quick Tips Brochure.

^‡Based on a study in which all 37 participants using the UnoReady Pen reported being satisfied or very satisfied with the device at 28 weeks for patients with moderate to severe plaque psoriasis.
^§Based on a study in which 30 of 38 participants using the UnoReady Pen reported no pain with the injection at 12 weeks.

gary — Individual results may vary. Gary was compensated for his time.

“The UPS guy shows up. I put my medicine away. When it’s the day to take it, I put it in. It's practically painless. I'm good to go. I don't think about it for a month, and then I'm excited to call to reorder to have the UPS guy show up again.”

Tap to see IMPORTANT SAFETY INFORMATION AND APPROVED USES

IMPORTANT SAFETY INFORMATION

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

What is the most important information I should know about COSENTYX?

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as…

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

What is the most important information I should know about COSENTYX?

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:

Infections

COSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections. Some people have died from these infections.

Your doctor should check you for tuberculosis (TB) before starting treatment with COSENTYX.
If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.
Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX. Do not use COSENTYX if you have an active TB infection.

Before starting COSENTYX, tell your doctor if you:

are being treated for an infection
have an infection that does not go away or that keeps coming back
have TB or have been in close contact with someone with TB
think you have an infection or have symptoms of an infection such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarrhea or stomach pain; burning when you urinate or urinate more often than normal

After starting COSENTYX, call your doctor right away if you have any signs of infection listed above. Do not use COSENTYX if you have any signs of infection unless you are instructed to by your doctor.

What are the possible side effects of COSENTYX?

COSENTYX may cause serious side effects, including:

Serious allergic reactions

Serious allergic reactions can occur. Get emergency medical help right away if you get any of the following symptoms: feeling faint; swelling of your face, eyelids, lips, mouth, tongue, or throat; trouble breathing or throat tightness; chest tightness; skin rash or hives (red, itchy bumps).

If you have a severe allergic reaction, do not give another injection of COSENTYX.

Inflammatory bowel disease

New cases of inflammatory bowel disease or "flare-ups" can happen with COSENTYX, and can sometimes be serious. If you have inflammatory bowel disease (ulcerative colitis or Crohn's disease), tell your doctor if you have worsening disease symptoms during treatment with COSENTYX or develop new symptoms of stomach pain or diarrhea.

Severe skin reactions that look like eczema can happen during treatment with COSENTYX from days to months after your first dose and can sometimes lead to hospitalization. Your doctor may temporarily stop treatment with COSENTYX if you develop severe skin reactions. Tell your doctor if you have any of the following signs or symptoms: redness or rash; itching; small bumps or patches; your skin is dry or feels like leather; blisters on the hands or feet that ooze or become crusty or skin peeling.

The most common side effects of COSENTYX include: cold symptoms, diarrhea, and upper respiratory tract infections.

These are not all of the possible side effects of COSENTYX. Call your doctor for medical advice about side effects.

Before using COSENTYX, tell your doctor if you:

have any of the conditions or symptoms listed above for infections.
have inflammatory bowel disease (Crohn's disease or ulcerative colitis).
are allergic to latex. The needle cap on the COSENTYX Sensoready® pen, and 150 mg/mL and 75 mg/0.5 mL prefilled syringes contains latex.
have recently received or are scheduled to receive an immunization (vaccine). People who take COSENTYX should not receive live vaccines. Children should be brought up to date with all vaccines before starting COSENTYX.
have any other medical conditions and all the medicines you take, including prescription and over‑the‑counter medicines, vitamins, and herbal supplements. Keep a list of your medicines to show your healthcare provider and pharmacist when you get a new medicine.
are pregnant or plan to become pregnant. It is not known if COSENTYX can harm your unborn baby. You and your doctor should decide if you will use COSENTYX.
are breastfeeding or plan to breastfeed. It is not known if COSENTYX passes into your breast milk.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch ↗, or call 1-800-FDA-1088.

Please see full Prescribing Information, including Medication Guide.

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Convenient once-a-month dosing†

The COSENTYX UnoReady® Pen is designed for comfortable use

The COSENTYX UnoReady Pen has a positive satisfaction rating up to 100%.‡

Individual results may vary. Gary was compensated for his time.

Convenient once-a-month dosing^†

The COSENTYX UnoReady Pen has a positive satisfaction rating up to 100%.^‡