How you manage your psoriatic arthritis pain can have a big impact on how you live your daily life. Managing more of the symptoms of PsA can help you put your best foot forward.

Biologics

What makes COSENTYX different?

There are multiple proteins in the body that may play a role in causing inflammation. The IL-17A protein is just one of them. COSENTYX is a different kind of targeted biologic. It’s the first and most prescribed treatment of its kind and works within your body to target IL-17A.

Across all indications.

 

What is a biologic?

A biologic is a protein-based medication that is made from living sources, and is taken by injection or infusion.

Here are the details

COSENTYX is proven to relieve more than just joint pain. It can help you find clearer skin, and also targets the pain that occurs where ligaments and tendons connect to the bone. This pain, known as enthesitis, commonly occurs in or around the elbows, knees, and heels. See the details below.

How does COSENTYX work?

Watch Dr. Elizabeth Perkins explain how COSENTYX works to help you feel better by targeting IL-17A within the body.

76% of patients had no radiographic progression

In the largest clinical trial ever conducted for psoriatic arthritis, COSENTYX was proven to help stop further joint damage

76% of patients taking COSENTYX had no increase in joint damage at 6 months§

Based on data from X-rays of the hands and feet at 6 months.
§For patients taking the 300-mg dose of COSENTYX. 71% of patients had no increase in joint damage at 6 months in the 150-mg group, versus 68% of patients taking placebo.

If left untreated, PsA can cause permanent joint damage, also known as radiographic progression

This can cause your joints, such as your fingers or toes, to become permanently damaged, and can disrupt your ability to perform daily activities. COSENTYX is proven to help stop further joint damage.

COSENTYX targets multiple symptoms of psoriatic arthritis, such as:

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Joint Pain and Swelling

“The mobility that I have in my hands, and my back and spine, has improved as well.”

—Joni, Actual Patient

Individual results may vary. Joni was compensated for her time.

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Psoriasis Skin Plaques

“It’s reduced my psoriasis dramatically.”

—Mike, Actual Patient

Individual results may vary. Mike was compensated for his time.

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Enthesitis Pain

Pain that occurs where ligaments and tendons connect to bones

“I have a lot less pain. The first sign was in my heel.”

—Darren, Actual Patient

Individual results may vary. Darren was compensated for his time.

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Dactylitis

Swelling of an entire finger or toe

“I got relief from the pain and the swelling in my hands.”

—Tina, Actual Patient

Individual results may vary. Tina was compensated for her time.

 

Find real relief from PsA. See our results at 16 weeks and at 4 years.

60%

Up to 60% of patients in a clinical trial saw at least a 20% improvement in PsA symptoms at 16 weeks.

Approximately 60% of patients taking COSENTYX saw this level of improvement versus 18% of patients taking placebo.

3 WKS

Some patients felt relief as early as 3 weeks.

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For patients who continued on COSENTYX for 4 years, a similar percentage saw an improvement in PsA symptoms.

In this study, patients and doctors were told which medication was being used after 6 months. When patients and doctors know the study drug being used, it may affect the results.

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Complete reduction of swelling

In a clinical trial, more than half of people with completely swollen fingers and toes (dactylitis) no longer had signs of swelling after 6 months of taking COSENTYX versus 16% for placebo.

Watch Me Now

Real people with active psoriatic arthritis are getting real relief with COSENTYX.

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Indications

COSENTYX® (secukinumab) is a prescription medicine used to treat adults:

  • with moderate to severe plaque psoriasis that involves large areas or many areas of the body, and who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light, alone or with systemic therapy)

  • with active psoriatic arthritis

  • with active ankylosing spondylitis

Important Safety Information

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:

Infections

COSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections.

  • Your doctor should check you for tuberculosis (TB) before starting treatment with COSENTYX.
  • If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.
  • Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX. Do not take COSENTYX if you have an active TB infection.

Before starting COSENTYX, tell your doctor if you:

  • are being treated for an infection
  • have an infection that does not go away or that keeps coming back
  • have TB or have been in close contact with someone with TB
  • think you have an infection or have symptoms of an infection, such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarrhea or stomach pain; burning when you urinate or urinate more often than normal

After starting COSENTYX, call your doctor right away if you have any signs of infection listed above. Do not use COSENTYX if you have any signs of infection unless you are instructed to by your doctor.

Inflammatory Bowel Disease

New cases of inflammatory bowel disease or “flare-ups” can happen with COSENTYX, and can sometimes be serious. If you have inflammatory bowel disease (ulcerative colitis or Crohn’s disease), tell your doctor if you have worsening disease symptoms during treatment with COSENTYX or develop new symptoms of stomach pain or diarrhea.

Serious Allergic Reactions

Serious allergic reactions can occur. Get emergency medical help right away if you get any of the following symptoms: feeling faint; swelling of your face, eyelids, lips, mouth, tongue, or throat; trouble breathing or throat tightness; chest tightness; or skin rash. If you have a severe allergic reaction, do not give another injection of COSENTYX.  

Before starting COSENTYX, tell your doctor if you:

  • have any of the conditions or symptoms listed above for infections
  • have inflammatory bowel disease (Crohn's disease or ulcerative colitis)
  • are allergic to latex. The needle caps contain latex.
  • have recently received or are scheduled to receive an immunization (vaccine). People who take COSENTYX should not receive live vaccines.
  • have any other medical conditions
  • are pregnant or plan to become pregnant. It is not known if COSENTYX can harm your unborn baby. You and your doctor should decide if you will use COSENTYX.
  • are breastfeeding or plan to breastfeed. It is not known if COSENTYX passes into your breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of your medicines to show your doctor and pharmacist when you get a new medicine.

How should I use COSENTYX?

See the detailed Instructions for Use that comes with your COSENTYX for information on how to prepare and inject a dose of COSENTYX, and how to properly throw away (dispose of) used COSENTYX Sensoready® pens and prefilled syringes.

  • Use COSENTYX exactly as prescribed by your doctor.
  • If your doctor decides that you or a caregiver may give your injections of COSENTYX at home, you should receive training on the right way to prepare and inject COSENTYX. Do not try to inject COSENTYX yourself, until you or your caregiver has been shown how to inject COSENTYX by your doctor or nurse.

The most common side effects of COSENTYX include: cold symptoms, diarrhea, and upper respiratory infections. These are not all of the possible side effects of COSENTYX. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

 Please see full Prescribing Information, including Medication Guide.