WATCH ME START MY JOURNEY

Individual results may vary.

Now that you've learned about COSENTYX® for ankylosing spondylitis, here's a reminder of the results you could expect.

COSENTYX IS PROVEN TO REDUCE SYMPTOMS OF ANKYLOSING SPONDYLITIS

  • AT
  • 16
  • WEEKS

6 OUT OF 10 PEOPLE NOTICED AT LEAST A

20%

IMPROVEMENT IN SYMPTOMS OF AS VERSUS 3 OUT OF 10 TAKING A PLACEBO

In clinical trials, at 16 weeks, approximately 6 out of 10 people noticed at least a 20% improvement in symptoms, and approximately 4 out of 10 people saw at least a 40% improvement in symptoms of AS versus 1 out of 10 taking a placebo.

At 16 weeks, some people taking COSENTYX in clinical trials experienced:

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BACK PAIN

MORNING STIFFNESS

COSENTYX CAN HELP IMPROVE YOUR MOBILITY SO YOU CAN MORE EASILY DO THE THINGS YOU NEED TO DO.

In a clinical trial with COSENTYX, patients completed a questionnaire that asked how difficult it was to perform daily activities, which included:

BENDING FROM THE WAIST TO PICK UP AN ITEM OFF THE FLOOR WITHOUT AN AID

DOING PHYSICALLY DEMANDING ACTIVITIES (SUCH AS GARDENING OR SPORTS)

DOING A FULL DAY OF ACTIVITIES AT WORK OR HOME

CLIMBING 12–15 STEPS WITHOUT USING A HANDRAIL OR WALKING AID

EXPERIENCE

COSENTYX has been studied in clinical trials for AS since 2011.

COSENTYX MAY HELP. IT'S THE FIRST OF ITS KIND.

COSENTYX is the first medicine of its kind for ankylosing spondylitis. Itís the only FDA-approved medication for ankylosing spondylitis that specifically targets IL-17A.

TAKING COSENTYX

COSENTYX is a once-a-month injection. Your doctor may prescribe 5 weekly doses to get you started if he or she thinks it's necessary. The recommended dose is 150 mg used under the skin.

$0 CO-PAY

You may be eligible for our $0 co-pay* program if you're commercially insured.

*Limitations apply. See program terms and conditions. For those commercially insured and 18 years or older. Up to a $16,000 annual cap. You will be responsible for any co-pay once limit is reached in a calendar year. This offer is not valid under Medicare, Medicaid, or any other federal or state program. Not valid for cash-paying patients. Novartis reserves the right to rescind, revoke, or amend this program without notice. Enrollment expires 12/31/17.

HEREíS THE

FORM TO GET

STARTED WITH

COSENTYX

Your doctor will

help you fill this out.

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IMPORTANT SAFETY INFORMATION

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Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:

Infections

COSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections.

  • Your doctor should check you for tuberculosis (TB) before starting treatment with COSENTYX.
  • If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.
  • Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX. Do not take COSENTYX if you have an active TB infection.

Before starting COSENTYX, tell your doctor if you:

  • are being treated for an infection
  • have an infection that does not go away or that keeps coming back
  • have TB or have been in close contact with someone with TB
  • think you have an infection or have symptoms of an infection such as:
  • fevers, sweats, or chills
  • muscle aches
  • cough
  • shortness of breath
  • blood in your phlegm
  • weight loss
  • warm, red, or painful skin or sores on your body
  • diarrhea or stomach pain
  • burning when you urinate or urinate more often than normal

After starting COSENTYX, call your doctor right away if you have any signs of infection listed above. Do not use COSENTYX if you have any signs of infection unless you are instructed to by your doctor.

Inflammatory Bowel Disease

New cases of inflammatory bowel disease or "flare-ups" can happen with COSENTYX, and can sometimes be serious. If you have inflammatory bowel disease (ulcerative colitis or Crohn’s disease), tell your doctor if you have worsening disease symptoms during treatment with COSENTYX or develop new symptoms of stomach pain or diarrhea.

Serious Allergic Reactions

Serious allergic reactions can occur. Get emergency medical help right away if you get any of the following symptoms: feeling faint; swelling of your face, eyelids, lips, mouth, tongue, or throat; trouble breathing or throat tightness; chest tightness; or skin rash. If you have a severe allergic reaction, do not give another injection of COSENTYX.

Before starting COSENTYX, tell your doctor if you:

  • have any of the conditions or symptoms listed above for infections
  • have inflammatory bowel disease (Crohn’s disease or ulcerative colitis)
  • are allergic to latex. The needle caps contain latex.
  • have recently received or are scheduled to receive an immunization (vaccine). People who take COSENTYX should not receive live vaccines.
  • have any other medical conditions
  • are pregnant or plan to become pregnant. It is not known if COSENTYX can harm your unborn baby. You and your doctor should decide if you will use COSENTYX.
  • are breastfeeding or plan to breastfeed. It is not known if COSENTYX passes into your breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of your medicines to show your doctor and pharmacist when you get a new medicine.

How should I use COSENTYX?

See the detailed Instructions for Use that comes with your COSENTYX for information on how to prepare and inject a dose of COSENTYX, and how to properly throw away (dispose of) used COSENTYX Sensoready® pens and prefilled syringes.

  • Use COSENTYX exactly as prescribed by your doctor.
  • If your doctor decides that you or a caregiver may give your injections of COSENTYX at home, you should receive training on the right way to prepare and inject COSENTYX. Do not try to inject COSENTYX yourself, until you or your caregiver has been shown how to inject COSENTYX by your doctor or nurse.
  • The most common side effects of COSENTYX include: cold symptoms, diarrhea, and upper respiratory infections. These are not all of the possible side effects of COSENTYX. Call your doctor for medical advice about side effects.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

INDICATION

COSENTYX® (secukinumab) is a prescription medicine used to treat adults with moderate to severe plaque psoriasis that involves large areas or many areas of the body, and who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light, alone or with systemic therapy).

Please see full Prescribing Information, including Medication Guide.