COSENTYX WORKS TO KEEP SKIN CLEAR

Clearer skin is important to you, and can make a big difference in how you live your life. And if you decide to try COSENTYX®, you want to see results that last.

Here’s what we found in clinical trials:

AT3MONTHS

THE MAJORITY OF PEOPLE WERE CLEAR OR ALMOST CLEAR.

APPROXIMATELY 8 OUT OF 10 PEOPLE SAW 75%SKIN CLEARANCE

APPROXIMATELY 6 OUT OF 10 PEOPLE SAW 90%SKIN CLEARANCE

Trial results for people taking the 300-mg dose of COSENTYX.

For some, a dose of 150 mg may be acceptable. For people taking the 150-mg dose, approximately 7 out of 10 saw 75% skin clearance and approximately 4 out of 10 saw 90% skin clearance.

Before photos from real patients in our clinical trials taking COSENTYX to treat moderate to severe plaque psoriasis
After photo from real patients in our clinical trials taking COSENTYX for moderate to severe plaque psoriasis for 3 months

Photos represent the average response seen with COSENTYX at 3 months. Individual results may vary.

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Among those moderate to severe plaque psoriasis patients who kept a symptom diary (670 people, or 39%), participants taking COSENTYX reported a reduction in pain, itching, and scaling, compared with those not taking COSENTYX in the studies (placebo).

AT
HOW DOES COSENTYX WORK
YEARS

THOSE WHO INITIALLY SAW RESULTS CONTINUED TO SEE THEM AT 2 YEARS.

MORE THAN 8 OUT OF 10 PEOPLE MAINTAINED 75%SKIN CLEARANCE

MORE THAN7 OUT OF 10 PEOPLE MAINTAINED 90%SKIN CLEARANCE

Trial results for people taking the 300-mg dose of COSENTYX.

For some, a dose of 150 mg may be acceptable. For people taking the 150-mg dose, approximately 7 out of 10 maintained 75% skin clearance, and approximately 5 out of 10 maintained 90% skin clearance.

EXPERIENCE

COSENTYX has been extensively studied in plaque psoriasis clinical trials since 2007.

  • More than 3400 people with moderate to severe plaque psoriasis participated
  • 10 clinical trials over the course of the plaque psoriasis trial program
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When my psoriasis was active, I had to cover myself when I didn't want attention. But now, I can wear my bright, fun, weird clothes that people are gonna stare at.” – SonyaSee Sonya’s storyIndividual results may vary.

WHY IS IL-17A IMPORTANT?

HOW IS COSENTYX DIFFERENT FROM OTHER MEDICATIONS FOR PLAQUE PSORIASIS?

COSENTYX is the first FDA-approved prescription medicine that selectively targets IL-17A.

HOW DOES COSENTYX WORK

WHAT IS IL-17A?

Plaque psoriasis is the result of an overactive immune system. Although the specific causes of plaque psoriasis are not fully known, it is believed that there are multiple proteins in your immune system, including IL-17A, that may play a role in inflammation and skin plaque growth.

IMPORTANT SAFETY INFORMATION

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Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:

Infections

COSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections.

  • Your doctor should check you for tuberculosis (TB) before starting treatment with COSENTYX.
  • If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.
  • Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX. Do not take COSENTYX if you have an active TB infection.

Before starting COSENTYX, tell your doctor if you:

  • are being treated for an infection
  • have an infection that does not go away or that keeps coming back
  • have TB or have been in close contact with someone with TB
  • think you have an infection or have symptoms of an infection such as:
  • fevers, sweats, or chills
  • muscle aches
  • cough
  • shortness of breath
  • blood in your phlegm
  • weight loss
  • warm, red, or painful skin or sores on your body
  • diarrhea or stomach pain
  • burning when you urinate or urinate more often than normal

After starting COSENTYX, call your doctor right away if you have any signs of infection listed above. Do not use COSENTYX if you have any signs of infection unless you are instructed to by your doctor.

Inflammatory Bowel Disease

New cases of inflammatory bowel disease or "flare-ups" can happen with COSENTYX, and can sometimes be serious. If you have inflammatory bowel disease (ulcerative colitis or Crohn’s disease), tell your doctor if you have worsening disease symptoms during treatment with COSENTYX or develop new symptoms of stomach pain or diarrhea.

Serious Allergic Reactions

Serious allergic reactions can occur. Get emergency medical help right away if you get any of the following symptoms: feeling faint; swelling of your face, eyelids, lips, mouth, tongue, or throat; trouble breathing or throat tightness; chest tightness; or skin rash. If you have a severe allergic reaction, do not give another injection of COSENTYX.

Before starting COSENTYX, tell your doctor if you:

  • have any of the conditions or symptoms listed above for infections
  • have inflammatory bowel disease (Crohn’s disease or ulcerative colitis)
  • are allergic to latex. The needle caps contain latex.
  • have recently received or are scheduled to receive an immunization (vaccine). People who take COSENTYX should not receive live vaccines.
  • have any other medical conditions
  • are pregnant or plan to become pregnant. It is not known if COSENTYX can harm your unborn baby. You and your doctor should decide if you will use COSENTYX.
  • are breastfeeding or plan to breastfeed. It is not known if COSENTYX passes into your breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of your medicines to show your doctor and pharmacist when you get a new medicine.

How should I use COSENTYX?

See the detailed Instructions for Use that comes with your COSENTYX for information on how to prepare and inject a dose of COSENTYX, and how to properly throw away (dispose of) used COSENTYX Sensoready® pens and prefilled syringes.

  • Use COSENTYX exactly as prescribed by your doctor.
  • If your doctor decides that you or a caregiver may give your injections of COSENTYX at home, you should receive training on the right way to prepare and inject COSENTYX. Do not try to inject COSENTYX yourself, until you or your caregiver has been shown how to inject COSENTYX by your doctor or nurse.
  • The most common side effects of COSENTYX include: cold symptoms, diarrhea, and upper respiratory infections. These are not all of the possible side effects of COSENTYX. Call your doctor for medical advice about side effects.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

INDICATION

COSENTYX® (secukinumab) is a prescription medicine used to treat adults with moderate to severe plaque psoriasis that involves large areas or many areas of the body, and who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light, alone or with systemic therapy).

Please see full Prescribing Information, including Medication Guide.